Soak the chicken pieces in buttermilk for at least an hour in the fridge.
In a large bowl, combine the flour, paprika, garlic powder, onion powder, salt, pepper, and cayenne pepper.
Remove the chicken from the buttermilk and let the excess drain off. Dredge each piece in the flour mixture to ensure it is well covered.
Preheat the air fryer to 390°F/199°C. Spray the air fryer basket with cooking spray.
Place the chicken pieces in the basket, taking care not to overcrowd. Coat the chicken lightly with cooking spray.
Cook for 25-30 minutes, flipping halfway through, until the chicken is golden brown and the internal temperature reaches 165°F (74°C).
Rest for a few minutes before serving. Enjoy your crispy, juicy air fryer-fried chicken!